抗体生产和表征

High-throughput antibodies from DNA to data

Get more shots on goal with industrial speed and consistent, reproducible yields. We combine high-velocity workflows with comprehensive data to accelerate your iterative discovery cycles.

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From sequence to validated candidates. All in one workflow.

Production that keeps pace with your pipeline

Move from sequence to purified protein in as few as 10 business days. With an industrial capacity of 6,000+ IgGs per week, we deliver the scalability and speed required to keep your discovery timeline on track.

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Characterize your antibodies with confidence

Get decision-ready data without the downstream delay. We integrate advanced characterization; including binding, purity, and stability, directly into our high-throughput workflow. Identify your best leads at the speed of your discovery.

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Data optimized for AI and ML integration

Let Twist handle the wet lab while your team focuses on AI. We deliver high-fidelity, model-ready datasets at industrial scale to fuel your discovery pipelines. Get the high-velocity, structured characterization your team needs to rank, train, and optimize candidates with confidence.

Explore AI drug discovery

Antibody Production Services

Produce your antibodies.
Propel your discovery.

High-throughput workflow

服务预期

Cell line options

Choose the right expression system for your discovery

From fast HEK-based screening to scalable CHO-based development.

HEK293

Lightning-fast discovery

  • 最佳选择: Early screening and hit ID
  • Key advantage: Maximum speed and adaptability
  • Turnaround: Starting at 10 business days*
  • 价格: Starting at $102 per purified IgG
CHO

The gold standard for Biopharma

  • 最佳选择: Therapeutic leads and scale-up
  • Key advantage: Established regulatory track record
  • Turnaround: Starting at 13 business days*
  • 价格: Starting at $102 per purified IgG
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Purification options

One platform, two paths to purification

His-Tagged (Ni-IMAC)

  • Best for scFv, Fab, VHH, and recombinant proteins
  • Very small (6xHis) tag that minimizes structural interference with the protein
  • Optimized for rapid affinity ranking and cell-based binding confirmation

Fc-Tagged (Protein A)

  • Best for full-length IgG and VHH-Fc formats
  • Large tag aids in protein solubility, stability, and proper folding
  • Move directly into high-sensitivity multi-point KD determination

Characterization Services

最快 15 个工作日获取表征数据

结合评估

Find your top binders

Screen large panels to identify antibodies with the strongest and most specific binding. Choose from binding confirmation, affinity, kinetics, and epitope binning.

Find your top binders
Identify your most stable and manufacturable candidates

可开发性

Identify your most stable and manufacturable candidates

Assess thermal stability via nanoDSF, predict aggregation and solubility with aSEC, AC-SINS, and DLS, and minimize off-target liabilities with polyreactivity and CIC screens — all in one integrated workflow.

高级表征

Go deeper with advanced characterization

Verify molecular weight via intact mass spec, ensure suitability for sensitive assays with endotoxin testing, and assess cross-reactivity and specificity across species models.

Go deeper with advanced characterization

应用

Versatility for any discovery application

AI/ML model training

Generate the standardized, high-volume datasets required to validate platforms and train predictive discovery algorithms.

Biotherapeutic development

Scale your biologic research with high-throughput production of therapeutic candidates or tool antibodies.

Diagnostic research & reagent discovery

Accelerate your path from DNA to data with flexible screening of candidate leads for diagnostic and reagent development programs.

Your next protein engineering innovation

Access specialized protein engineering expertise, high-throughput production, and advanced characterization without the need for internal lab space or infrastructure investment.

蛋白质的作用

Success stories and studies featuring Twist Antibodies

Deep Repertoire Mining Uncovers Ultra-Broad Coronavirus-Neutralizing Antibodies

9,000+

Antibodies identified

239

Antibodies expressed and characterized at scale

Discover how high-throughput antibody production and SPR-based epitope binning enabled researchers to mine ultra-rare, broadly neutralizing coronavirus antibodies from recovered and vaccinated patient samples.

使用产品

High Throughput Antibodies Affinity Ranking, Epitope Binning
阅读应用指南

Deep Repertoire Mining Uncovers Ultra-Broad Coronavirus-Neutralizing Antibodies

1/3

为什么选择 Twist?

One end-to-end trusted partner

Antibody production and characterization delivered with the same quality and reliability you expect from Twist.

Scalable from one to thousands

Whether you're running a few candidates or thousands for AI model training, Twist's high-throughput infrastructure supports consistent turnaround and performance at any volume.

Scientific expertise

Work directly with scientists to design and analyze your data from defining project scope, to screening set-up and interpreting data results.

Outsource with confidence

将 Twist 作为您的外部研发引擎,您无需投资内部设备、实验室空间或人员配备,即可满足精准度需求并获得专业知识。

我们的抗体和服务只是工作流程的一部分

将我们的高通量抗体和服务与全系列多用途 Twist 解决方案搭配使用。

Consult with an expert

与值得信赖的科学合作伙伴携手,指导您的项目规格。从定制数据配置到工作流程设计,我们的专家为您提供所需的前瞻性支持,以减少每个环节的阻力。

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