Genes
Oligo Pools
NGS
Variant Libraries
Antibodies
IVDR Solutions
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NEW
Introducing the Twist TrueAmp and PCR-Free WGS Library Preparation Kits.
Power your sequencing with Twist’s enzyme driven library prep; engineered to deliver more data from your sample, in any workflow.
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NGS Workflows
Crop and
Livestock
Improvement
From low-pass exploration to deep coverage precision, Twist empowers researchers to execute and scale whole genome sequencing with accuracy they can trust.
NGS
Optimized
Enzymes
Twist’s library prep kits use AI/ML-engineered proprietary enzymes to deliver purpose-built, reliable, and consistently superior NGS results.
Superior
Performance
for
High
Quality
Data
Get more insights with Twist’s high-yield, high-complexity libraries that boost depth, cut duplicates, and improve coverage.
Flexible
Workflows
for
Any
Application
With a full range of tailored library prep kits and adapters, Twist ensures you get the data you need.
With a WES solution built on intelligently designed exome panels and optimized enrichment, Twist delivers highly uniform, on-target coverage of clinically relevant coding and noncoding regions.
Efficient
by
Design
Twist exome panels focus sequencing on clinically relevant regions, improving efficiency while reducing sequencing and analysis costs.
Better
Probes,
Better
Panels
All Twist panels use dsDNA probes engineered for consistent hybridization and uniform coverage across diverse samples.
Endlessly
Adaptable
Twist Exome spike-ins boost coverage of disease-specific or custom targets, enhancing depth and performance without disrupting your workflow.
Twist’s custom DNA enrichment panels deliver tailored, high precision solutions, with expert bioinformatics support for exceptional performance.
Exceptional,
Consistent
Performance
High fidelity double stranded DNA probes with NGS based quality control ensures balanced probe representation and minimizes dropout.
Panel
Blending
Simplify your genomics workflow by combining two or more panels into a single, cohesive assay; either seamlessly in your own lab or with Twist handling the integration for you.
Scalable
Cover exactly the regions you need in your genomic regions of interest; with designs ranging from as few as 100 probes to well over one million.
Sustainability
and
Environmental
Resilience
Twist RNA-Seq solutions, designed for demanding samples such as low input and FFPE so you can get high quality libraries with high yield in a short workflow so you can get results.
Optimized
RNA-Seq
for
Tough,
Low-Input
Samples
Twist RNA-Seq workflows generate high-quality, uniform libraries, ensuring reliable transcriptome coverage even with challenging material.
Rapid
RNA-Seq
That
Doesn’t
Sacrifice
Quality
Twist’s fast-protocol RNA-Seq speeds library prep and turnaround while preserving coverage and data quality.
Comprehensive,
fast
whole-transcriptome
RNA-Seq
from
any
sample
Twist Whole Transcriptome RNA Library Prep delivers unbiased, high-quality libraries from total RNA; including FFPE, degraded, or low input sample.
RNA enrichment panels capture cDNA libraries for NGS, with exon-aware designs that deliver deeper, more informative transcription insights.
RNA
Exome
Panel:
More
Targets,
Fewer
Reads
RNA Exome focuses sequencing on protein coding transcripts to enable sensitive detection of low expressing genes while preserving isoform and junction information.
RNA
Fusion
Panel:
Confidently
Enrich
RNA
Gene
Fusions
The Twist RNA Fusion Panel Kit is an RNA based enrichment panel that enables more sensitive and targeted detection of gene fusions than conventional methods.
Custom
RNA
Panel:
Target
Exactly
What
Matters.
Capture transcriptomic data with a customized RNA panel; designed to capture and enrich libraries, to provide you with the transcriptomic insights you need
Therapeutic
Development
Twist’s methylation sequencing delivers high quality libraries and targeted panels that preserve DNA integrity and maximize CpG recovery.
High
Quality,
Low-Damage
Libraries
Enzymatic conversion and Twist’s optimized library prep preserve DNA integrity, producing higher complexity libraries and reliable results from challenging, low input samples.
More
CpGs,
Better
Resolution
The workflow supports detection of up to ~15% more CpGs than traditional bisulfite based methods, improving coverage of biologically important regions.
Adaptable
for
Existing
Methyl-Seq
Pipelines
Twist’s methylation library workflow fits seamlessly into standard NGS and methyl-seq pipelines without major protocol changes.
Twist’s methylation sequencing delivers high quality libraries and targeted panels that preserve DNA integrity and maximize CpG recovery.
Human
Methylome
Panel:
Broad
CpG
coverage
Expansive content makes this panel ideal for investigating methylation fractions across applications including cancer metastasis, human development, and functional genomics.
Twist
Pan
Cancer
Methylation
Panel
A cancer specific methylation panel, focused on methylation targets relevant to 31 different cancers.
Custom
Methylation
Panels:
Smarter
Design,
Better
Data
Custom DNA methylation panels enable high uniformity capture while preserving native methylation patterns through a four probe design targeting fully methylated, unmethylated, sense, and antisense sequences.
